Back to Insights
Productivity9 min read

Microsoft 365 Security: 10 Must-Have Configurations

Essential security settings every Microsoft 365 administrator should implement to protect company data.

December 20, 2025 · SPADES IT SOLUTIONS Team
Microsoft 365 Security

Microsoft 365 is the backbone of productivity for millions of businesses, but its default security settings leave significant gaps. These 10 configurations will dramatically improve your security posture.

1

Enable Multi-Factor Authentication (MFA)

Require MFA for all users, especially administrators. Use the Microsoft Authenticator app or hardware keys for the strongest protection.

2

Configure Conditional Access Policies

Block sign-ins from risky locations, require compliant devices, and enforce MFA based on user risk level.

3

Disable Legacy Authentication

Legacy protocols like POP3 and IMAP don't support MFA. Block them to prevent credential-based attacks.

4

Enable Audit Logging

Turn on unified audit logging to track user and admin activities. Essential for compliance and incident investigation.

5

Configure Data Loss Prevention (DLP)

Prevent sensitive data from leaving your organization via email, Teams, or SharePoint.

6

Set Up Safe Attachments and Safe Links

Scan attachments and URLs in real-time to block malware and phishing attempts.

7

Enable Mailbox Auditing

Track mailbox access and actions to detect compromised accounts and insider threats.

8

Configure External Sharing Settings

Limit SharePoint and OneDrive external sharing to approved domains or disable it entirely.

9

Implement Sensitivity Labels

Classify and protect documents based on sensitivity. Apply encryption and access controls automatically.

10

Review Admin Roles Regularly

Minimize the number of global administrators. Use role-based access control with just-in-time access.

Implementation Priority

Start with MFA and disabling legacy authentication - these alone prevent over 99% of account compromises. Then implement conditional access and audit logging. The remaining configurations can be phased in based on your compliance requirements and resources.

Need Help Securing Microsoft 365?

Our team can audit your current configuration and implement these security controls with minimal disruption to your users.

Request a Security Audit